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DAY 1

There was no significant difference between the groups in FEV1 increase as well:

+9.0±6.0% pred. in the Study Simeox group and + 8.0 ± 2.9 % pred. in the Control group (р=0.751) (Fig.1)

Fig.1 FEV1 changes (%pred) in the Study group (blue) and the Control group (green) after 5-day course of treatment.

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DAY 5

FEV1 %

15