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Conclusions

Patients with various chronic obstructive lung diseases acquired quickly autonomous usage of the device during hospitalization

after a short training by physiotherapists. The technology was very well tolerated in all patients who find it comfortable and easy

to use. No significant side effect related to Simeox device was reported in the series. These data confirm the feasibility and safety

of Simeox technology in patients suffering of bronchial congestion and requiring chest physiotherapy.

Mucus clearance and respiratory symptoms improved to the same extent as manual physiotherapy after a few days of therapy.

In some series, mucus production was increased with Simeox after manual physiotherapy trial. These results suggest that Simeox

can do as much or better than conventional physiotherapy for airway clearance management in patients hospitalized for acute

exacerbation and are in favor of promoting this technology as an alternative of conventional ACTs.

Moreover, Simeox device may provide also additional benefits on lung function and quality of life in patients with COPD and/or

bronchiectasis. These interesting data deserve to be investigated in more detail in the near future to understand deeply the

benefits of Simeox technology.

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