TriniCLOT PC II

The TriniCLOT PC II kit is intended for the quantitative measurement of the functional protein C level based on the prolongation of the Activated Partial Thromboplastin Time (aPTT).

In this assay, Protein C is activated in the presence of the specific activator extracted from Agkistrodon c. contortrix venom. The resulting activated protein C inhibits the factors V and VIII, and thus prolongs the aPTT of a system in which all the factors are present, constant and in excess (provided by the Reagent 1), except the protein C which is derived from the sample being tested.

TriniCLOT PS II

The TriniCLOT PS II kit is intended for the quantitative measurement of the functional protein S level based on the principle of factor Va inhibition. The principle of the assay is based upon the cofactor activity of protein S which enhances the anticoagulant action of activated protein C. This enhancement is reflected by the prolongation of the clotting time of a system

enriched with factor Va which is a physiological substrate for activated protein C.

TriniCLOT Lupus Screen and Confirm

TriniCLOT Lupus Screen and TriniCLOT Lupus Confirm are simplified dilute Russell s Viper Venom Time (dRVVT) reagents, intended to specifically detect Lupus Anticoagulants (LAs), a type of anti-phospholipid antibody. The reagents are simple one step clotting tests that can be performed either manually or on automated coagulation instruments.

Mixing tests may be used to exclude Factor II, V and X deficiencies that may prolong TriniCLOT Lupus Screen and TriniCLOT Lupus Confirm results.

TriniCLOT Speciality Reagents

PART NUMBER PRODUCT NAME STABILITY

T1607

TriniCLOT PC II

Reagent 1 (TriniCLOT PC Def Plasma): 3 x 1 mL 8 hours on board stability

Reagent 2 (TriniCLOT PC Activator): 3 x 1 mL 8 hours on board stability

PART NUMBER PRODUCT NAME STABILITY

T1608

TriniCLOT PS II

Reagent 1 (TriniCLOT PS Def Plasma): 2 x 1 mL 4 hours on board stability

Reagent 2 (TriniCLOT PS PCa): 2 x 1 mL 4 hours on board stability

Reagent 3 (TriniCLOT PS Factor Va): 2 x 1 mL 4 hours on board stability

PART NUMBER PRODUCT NAME PACKAGING STABILITY

T1604 TriniCLOT Lupus Screen 10 x 2 mL 48 hours at 2-8ºC

T1605 TriniCLOT Lupus Confirm 10 x 1 mL 48 hours at 2-8ºC

T4203 TriniCHECK Lupus Positive Control 6 x 1 mL 8 hours at 2-8ºC

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