TRAUMEEL® PRODUCT MONOGRAPH26

How is the AIR organized? The AIR is organized into three layers of structure and function (Figure 7). The top layer is the Phenotype layer, the middle layer is the Process layer, and the bottom layer is the Molecular Interaction Map (MIM). Changes on one layer have an effect and can be visualized on all other layers.

The Phenotype layer (top) shows cells and mediators. Clinicians are generally interested in connecting their patients to this layer. The Process layer (middle) describes key molecules / pathways regulating the top layer and is suitable for research scientists, looking to generate new hypothesis on the mechanistic insights of disease phenotype regulation. The MIM layer (bottom) depicts all molecular details and interactions in acute inflammation and IR. This layer is suitable for data integration and analysis, i.e. experimental data can be mapped onto this layer and then analyzed and visualized.

Clinical support for proresolution and tissue healing effects of Traumeel® Recent clinical evaluations of postoperative recovery suggest that use of Traumeel® can promote enhanced tissue recovery and facilitate faster return of function.[Das 2019, Helei 2019]

Post-periodontal surgery[Das 2019]

Prospective, randomized, triple-blind split-mouth clinical trial in 20 patients. Patients receiving Traumeel® experienced significantly less pain than those

receiving ibuprofen. Consumption of Traumeel® was also lower compared with ibuprofen. Compared with patients receiving ibuprofen, Traumeel® resulted in significantly

less edema and improved tissue colour, indicating improved tissue healing.

Figure 7 Atlas of Inflammation Resolution[Serhan 2020]